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Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK knockout mice
While the acute inhibitory effect of opioids on locus coeruleus (LC) neurons is mediated primarily by the activation of G protein-gated inwardly-rectifying K(+) (GIRK) channels, the 3′-5′-cyclic adenosine monophosphate (cAMP)-system has been implicated in the effects of chronic morphine exposure. Pr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582177/ https://ncbi.nlm.nih.gov/pubmed/18702733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06348.x |
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