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Deletion of GIRK2 Subunit of GIRK Channels Alters the 5-HT(1A) Receptor-Mediated Signaling and Results in a Depression-Resistant Behavior

BACKGROUND: Targeting dorsal raphe 5-HT(1A) receptors, which are coupled to G-protein inwardly rectifying potassium (GIRK) channels, has revealed their contribution not only to behavioral and functional aspects of depression but also to the clinical response to its treatment. Although GIRK channels...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Llamosas, Nerea, Bruzos-Cidón, Cristina, Rodríguez, José Julio, Ugedo, Luisa, Torrecilla, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756724/
https://ncbi.nlm.nih.gov/pubmed/25956878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv051
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