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Deletion of GIRK2 Subunit of GIRK Channels Alters the 5-HT(1A) Receptor-Mediated Signaling and Results in a Depression-Resistant Behavior
BACKGROUND: Targeting dorsal raphe 5-HT(1A) receptors, which are coupled to G-protein inwardly rectifying potassium (GIRK) channels, has revealed their contribution not only to behavioral and functional aspects of depression but also to the clinical response to its treatment. Although GIRK channels...
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| Publié dans: | Int J Neuropsychopharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756724/ https://ncbi.nlm.nih.gov/pubmed/25956878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv051 |
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