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The Inwardly Rectifying K(+) Channel Subunit GIRK1 Rescues the GIRK2 weaver Phenotype

The weaver (wv) gene has been identified as a glycine to serine substitution at residue 156 in the H5 region of inwardly rectifying K(+) channel, GIRK2. The mutation is permissive for the expression of homotetrameric channels that are nonselective for cations and G-protein-independent. Coexpression...

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Pubblicato in:J Neurosci
Autori principali: Hou, Ping, Yan, Shuizhong, Tang, Weijen, Nelson, Deborah J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783034/
https://ncbi.nlm.nih.gov/pubmed/10493734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08327.1999
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