N‐Acetylcysteine, a glutathione precursor, reverts vascular dysfunction and endothelial epigenetic programming in intrauterine growth restricted guinea pigs

KEY POINTS: Intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial epigenetic programming of the umbilical vessels. There is no evidence that this epigenetic programming is occurring on systemic fetal arteries. In IUGR guinea pigs we...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Herrera, Emilio A., Cifuentes‐Zúñiga, Francisca, Figueroa, Esteban, Villanueva, Cristian, Hernández, Cherie, Alegría, René, Arroyo‐Jousse, Viviana, Peñaloza, Estefania, Farías, Marcelo, Uauy, Ricardo, Casanello, Paola, Krause, Bernardo J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309367/
https://ncbi.nlm.nih.gov/pubmed/27739590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273396
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