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Altering intracellular pH reveals the kinetic basis of intraburst gating in the CFTR Cl(−) channel
KEY POINTS: The cystic fibrosis transmembrane conductance regulator (CFTR), which is defective in the genetic disease cystic fibrosis (CF), forms a gated pathway for chloride movement regulated by intracellular ATP. To understand better CFTR function, we investigated the regulation of channel openin...
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| Udgivet i: | J Physiol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5309365/ https://ncbi.nlm.nih.gov/pubmed/27779763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273205 |
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