Shear-Mediated Platelet Activation in the Free Flow: Perspectives on the Emerging Spectrum of Cell Mechanobiological Mechanisms Mediating Cardiovascular Implant Thrombosis

Shear-mediated platelet activation (SMPA) is central in thrombosis of implantable cardiovascular therapeutic devices. Despite the morbidity and mortality associated with thrombosis of these devices, our understanding of mechanisms operative in SMPA, particularly in free flowing blood, remains limite...

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Detalhes bibliográficos
Publicado no:J Biomech
Main Authors: Slepian, Marvin J., Sheriff, Jawaad, Hutchinson, Marcus, Tran, Phat, Bajaj, Naing, Garcia, Joe G.N., Saavedra, S. Scott, Bluestein, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309211/
https://ncbi.nlm.nih.gov/pubmed/27887727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2016.11.016
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