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High-Shear Stress Sensitizes Platelets to Subsequent Low-Shear Conditions

Individuals with mechanical heart valve implants are plagued by flow-induced thromboembolic complications, which are undoubtedly caused by platelet activation. Flow fields in or around the affected regions involve brief exposure to pathologically high-shear stresses on the order of 100 to 1000 dyne/...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sheriff, Jawaad, Bluestein, Danny, Girdhar, Gaurav, Jesty, Jolyon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872093/
https://ncbi.nlm.nih.gov/pubmed/20135353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-010-9936-2
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