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Benzimidazopurine nucleosides from N(6)-aryl adenosine derivatives by PhI(OAc)(2)-mediated C–N bond formation, no metal needed

The reaction of a variety N(6)-aryl 2’-deoxyadenosine and adenosine derivatives with PhI(OAc)(2) in 1,1,1,3,3,3-hexafluoro-2-propanol provides facile access to benzimidazopurine nucleoside analogues by metal-free C–N bond formation with a purinyl nitrogen atom. These reactions likely proceed via rad...

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Publicado en:Chem Commun (Camb)
Autores principales: Satishkumar, Sakilam, Lakshman, Mahesh K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309161/
https://ncbi.nlm.nih.gov/pubmed/27976760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc07722f
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