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An Expedient Procedure for the Oxidative Cleavage of Olefinic Bonds with PhI(OAc)(2), NMO, and Catalytic OsO(4)

[Image: see text] PhI(OAc)(2) in the presence of OsO(4) (cat.) and 2,6-lutidine cleaves olefinic bonds to yield the corresponding carbonyl compounds, albeit, in some cases, with α-hydroxy ketones as by-products. A more practical and clean protocol to effect oxidative cleavage of olefinic bonds invol...

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Detalhes bibliográficos
Main Authors: Nicolaou, K. C., Adsool, Vikrant A., Hale, Christopher R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848477/
https://ncbi.nlm.nih.gov/pubmed/20192259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100290a
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