Sulforaphane-induced apoptosis involves the type 1 IP(3) receptor

In this study we show that anti-tumor effect of sulforaphane (SFN) is partially realized through the type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1). This effect was verified in vitro on three different stable cell lines and also in vivo on the model of nude mice with developed tumors. Early...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hudecova, Sona, Markova, Jana, Simko, Veronika, Csaderova, Lucia, Stracina, Tibor, Sirova, Marta, Fojtu, Michaela, Svastova, Eliska, Gronesova, Paulina, Pastorek, Michal, Novakova, Marie, Cholujova, Dana, Kopacek, Juraj, Pastorekova, Silvia, Sedlak, Jan, Krizanova, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308660/
https://ncbi.nlm.nih.gov/pubmed/27528021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8968
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