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The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer
Gemcitabine (GEM) resistance is a critical issue for pancreatic cancer treatment. The involvement of epigenetic modification in GEM resistance is still unclear. We established a GEM-resistant subline PANC-1-R from the parental PANC-1 pancreatic cancer cells and found the elevation of various chromat...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308641/ https://ncbi.nlm.nih.gov/pubmed/27531902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11256 |
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