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Protein Arginine Methyltransferase 3 Enhances Chemoresistance in Pancreatic Cancer by Methylating hnRNPA1 to Increase ABCG2 Expression

Pancreatic cancer is poorly responsive to chemotherapy due to intrinsic or acquired resistance. Our previous study showed that epigenetic modifying enzymes including protein arginine methyltransferase 3 (PRMT3) are dysregulated in gemcitabine (GEM)-resistant pancreatic cancer cells. Here, we attempt...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancers (Basel)
Main Authors: Hsu, Ming-Chuan, Pan, Mei-Ren, Chu, Pei-Yi, Tsai, Ya-Li, Tsai, Chia-Hua, Shan, Yan-Shen, Chen, Li-Tzong, Hung, Wen-Chun
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356582/
https://ncbi.nlm.nih.gov/pubmed/30577570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010008
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