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Interleukin-6 increases matrix metalloproteinase-14 (MMP-14) levels via down-regulation of p53 to drive cancer progression

Matrix metalloproteinases (MMPs) play critical roles in cancer invasion and metastasis by digesting basement membrane and extracellular matrix (ECM). Much attention has focused on the enzymatic activities of MMPs; however, the regulatory mechanism of MMP expression remains elusive. By employing bioi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cathcart, Jillian M., Banach, Anna, Liu, Alice, Chen, Jun, Goligorsky, Michael, Cao, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308639/
https://ncbi.nlm.nih.gov/pubmed/27531896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11243
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