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Differential control of retrovirus silencing in embryonic cells by proteasomal regulation of the ZFP809 retroviral repressor
Replication of the murine leukemia viruses is strongly suppressed in mouse embryonic stem (ES) cells. Proviral DNAs are formed normally but are then silenced by a large complex bound to DNA by the ES cell-specific zinc-finger protein ZFP809. We show here that ZFP809 expression is not regulated by tr...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307487/ https://ncbi.nlm.nih.gov/pubmed/28115710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620879114 |
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