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Direct measurement of sequence-dependent transition path times and conformational diffusion in DNA duplex formation

The conformational diffusion coefficient, D, sets the timescale for microscopic structural changes during folding transitions in biomolecules like nucleic acids and proteins. D encodes significant information about the folding dynamics such as the roughness of the energy landscape governing the fold...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Neupane, Krishna, Wang, Feng, Woodside, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307458/
https://ncbi.nlm.nih.gov/pubmed/28115714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611602114
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