Hematopoietic pannexin 1 function is critical for neuropathic pain

Neuropathic pain symptoms respond poorly to available therapeutics, with most treated patients reporting unrelieved pain and significant impairment in daily life. Here, we show that Pannexin 1 (Panx1) in hematopoietic cells is required for pain-like responses following nerve injury in mice, and a po...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weaver, Janelle L., Arandjelovic, Sanja, Brown, Gregory, K. Mendu, Suresh, S. Schappe, Michael, Buckley, Monica W., Chiu, Yu-Hsin, Shu, Shaofang, Kim, Jin K., Chung, Joyce, Krupa, Julia, Jevtovic-Todorovic, Vesna, Desai, Bimal N., Ravichandran, Kodi S., Bayliss, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307344/
https://ncbi.nlm.nih.gov/pubmed/28195232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42550
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