Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro

During prolonged hypoxic conditions, endothelial cells change their gene expression to adjust to the low oxygen environment. This process is mainly regulated by the hypoxia-inducible factors, HIF-1α and HIF-2α. Although endothelial cells do not form sprouts during prolonged hypoxic culturing, silenc...

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Detalhes bibliográficos
Publicado no:Angiogenesis
Main Authors: Nauta, Tessa D., van den Broek, Marloes, Gibbs, Sue, van der Pouw-Kraan, Tineke C. T. M., Oudejans, Cees B., van Hinsbergh, Victor W. M., Koolwijk, Pieter
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306362/
https://ncbi.nlm.nih.gov/pubmed/27699500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-016-9527-4
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