Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential

Vascular homeostasis and regeneration in ischemic tissue relies on intrinsic competence of the tissue to rapidly recruit endothelial cells for vascularization. The mononuclear cell (MNC) fraction of blood contains circulating progenitors committed to endothelial lineage. These progenitors give rise...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Tasev, Dimitar, Dekker-Vroling, Laura, van Wijhe, Michiel, Broxterman, Henk J., Koolwijk, Pieter, van Hinsbergh, Victor W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306419/
https://ncbi.nlm.nih.gov/pubmed/30619865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00356
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