Importance of detoxifying enzymes in differentiating fibrotic development between SHRSP5/Dmcr and SHRSP rats

OBJECTIVES: High-fat and -cholesterol diet (HFC) induced fibrotic steatohepatitis in stroke-prone spontaneously hypertensive rat (SHRSP) 5/Dmcr, the fifth substrain from SHRSP, by dysregulating bile acid (BA) kinetics. This study aimed to clarify the histopathological and BA kinetic differences in H...

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Detalhes bibliográficos
Publicado no:Environ Health Prev Med
Main Authors: Naito, Hisao, Jia, Xiaofang, Yetti, Husna, Yanagiba, Yukie, Tamada, Hazuki, Kitamori, Kazuya, Hayashi, Yumi, Wang, Dong, Kato, Masashi, Ishii, Akira, Nakajima, Tamie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2016
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305991/
https://ncbi.nlm.nih.gov/pubmed/27209494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12199-016-0539-x
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