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Dysregulated Bile Acid Synthesis, Metabolism and Excretion in a High Fat-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats

BACKGROUND AND AIMS: Cholesterol over-intake is involved in the onset of nonalcoholic steatohepatitis (NASH), and hepatocellular bile acid (BA) accumulation correlates with liver injuries. However, how dietary cholesterol influences cholesterol and BA kinetics in NASH liver remains ambiguous and nee...

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Detalhes bibliográficos
Main Authors: Jia, Xiaofang, Naito, Hisao, Yetti, Husna, Tamada, Hazuki, Kitamori, Kazuya, Hayashi, Yumi, Wang, Dong, Yanagiba, Yukie, Wang, Juncai, Ikeda, Katsumi, Yamori, Yukio, Nakajima, Tamie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731517/
https://ncbi.nlm.nih.gov/pubmed/23824403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-013-2747-1
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