Simultaneous changes in high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis and those underlying molecular mechanisms in novel SHRSP5/Dmcr rat

OBJECTIVES: The aim of this study was to identify the molecular mechanisms underlying high-fat and high-cholesterol (HFC) diet-induced steatohepatitis and associated liver fibrosis progression in a novel stroke-prone, spontaneously hypertensive 5/Dmcr (SHRSP5/Dmcr) rat model. METHODS: SHRSP5/Dmcr ra...

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Detalhes bibliográficos
Main Authors: Moriya, Takashi, Kitamori, Kazuya, Naito, Hisao, Yanagiba, Yukie, Ito, Yuki, Yamagishi, Nozomi, Tamada, Hazuki, Jia, Xiaofang, Tsuchikura, Satoru, Ikeda, Katsumi, Yamori, Yukio, Nakajima, Tamie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493629/
https://ncbi.nlm.nih.gov/pubmed/22407906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12199-012-0273-y
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