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Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes

Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 di...

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Bibliographische Detailangaben
Veröffentlicht in:Diab Vasc Dis Res
Hauptverfasser: Riches, Kirsten, Huntriss, John, Keeble, Claire, Wood, Ian C, O’Regan, David J, Turner, Neil A, Porter, Karen E
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305035/
https://ncbi.nlm.nih.gov/pubmed/28185533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1479164116677968
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