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Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes

Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 di...

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Vydáno v:Diab Vasc Dis Res
Hlavní autoři: Riches, Kirsten, Huntriss, John, Keeble, Claire, Wood, Ian C, O’Regan, David J, Turner, Neil A, Porter, Karen E
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305035/
https://ncbi.nlm.nih.gov/pubmed/28185533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1479164116677968
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