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Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes

Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 di...

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Detalhes bibliográficos
Publicado no:Diab Vasc Dis Res
Main Authors: Riches, Kirsten, Huntriss, John, Keeble, Claire, Wood, Ian C, O’Regan, David J, Turner, Neil A, Porter, Karen E
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305035/
https://ncbi.nlm.nih.gov/pubmed/28185533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1479164116677968
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