Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function

Type 2 diabetes (T2DM) promotes premature atherosclerosis and inferior prognosis after arterial reconstruction. Vascular smooth muscle cells (SMC) respond to patho/physiological stimuli, switching between quiescent contractile and activated synthetic phenotypes under the control of microRNAs (miRs)...

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Hlavní autoři: Riches, Kirsten, Alshanwani, Aliah R., Warburton, Philip, O’Regan, David J., Ball, Stephen G., Wood, Ian C., Turner, Neil A., Porter, Karen E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121534/
https://ncbi.nlm.nih.gov/pubmed/24927876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.05.018
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