The kinesin KIF21B regulates microtubule dynamics and is essential for neuronal morphology, synapse function and learning and memory

The kinesin KIF21B is implicated in several human neurological disorders including delayed cognitive development, yet it remains unclear how KIF21B dysfunction may contribute to pathology. One limitation is that relatively little is known about KIF21B-mediated physiological mechanisms. Here, we gene...

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Udgivet i:Cell Rep
Main Authors: Muhia, Mary, Thies, Edda, Labonté, Dorthe, Ghiretti, Amy E., Gromova, Kira V., Xompero, Francesca, Lappe-Siefke, Corinna, Hermans-Borgmeyer, Irm, Kuhl, Dietmar, Schweizer, Michaela, Ohana, Ora, Schwarz, Jürgen R., Holzbaur, Erika L.F., Kneussel, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305027/
https://ncbi.nlm.nih.gov/pubmed/27117409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.086
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