The kinesin KIF21B regulates microtubule dynamics and is essential for neuronal morphology, synapse function and learning and memory

The kinesin KIF21B is implicated in several human neurological disorders including delayed cognitive development, yet it remains unclear how KIF21B dysfunction may contribute to pathology. One limitation is that relatively little is known about KIF21B-mediated physiological mechanisms. Here, we gene...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Muhia, Mary, Thies, Edda, Labonté, Dorthe, Ghiretti, Amy E., Gromova, Kira V., Xompero, Francesca, Lappe-Siefke, Corinna, Hermans-Borgmeyer, Irm, Kuhl, Dietmar, Schweizer, Michaela, Ohana, Ora, Schwarz, Jürgen R., Holzbaur, Erika L.F., Kneussel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305027/
https://ncbi.nlm.nih.gov/pubmed/27117409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.086
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