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Modulation of the coagulation cascade using aptamers

As a novel class of therapeutics, aptamers, or nucleic acid ligands, have garnered clinical interest due to the ease of isolating a highly specific aptamer against a wide range of targets, their chemical flexibility and synthesis, as well as their inherent ability to have their inhibitory ability re...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Woodruff, Rebecca S, Sullenger, Bruce A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304947/
https://ncbi.nlm.nih.gov/pubmed/26315404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.300131
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