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Novel Small Molecule Probes for Metastatic Melanoma

[Image: see text] Actively targeting probe 1b, an unsymmetrical bivalent dipeptide mimic, selectively bound melanoma over healthy skin tissue in histological samples from patients and Sinclair swine. Modifications to 1b gave agents 2–4 that contain a near-IR aza-BODIPY fluor. Contrary to our expecta...

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Publicat a:ACS Med Chem Lett
Autors principals: Kamkaew, Anyanee, Fu, Nanyan, Cai, Weibo, Burgess, Kevin
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304293/
https://ncbi.nlm.nih.gov/pubmed/28197308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00368
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