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Novel Small Molecule Probes for Metastatic Melanoma

[Image: see text] Actively targeting probe 1b, an unsymmetrical bivalent dipeptide mimic, selectively bound melanoma over healthy skin tissue in histological samples from patients and Sinclair swine. Modifications to 1b gave agents 2–4 that contain a near-IR aza-BODIPY fluor. Contrary to our expecta...

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Bibliografische gegevens
Gepubliceerd in:ACS Med Chem Lett
Hoofdauteurs: Kamkaew, Anyanee, Fu, Nanyan, Cai, Weibo, Burgess, Kevin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2016
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304293/
https://ncbi.nlm.nih.gov/pubmed/28197308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00368
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