Transient Dysregulation of Dopamine Signaling in a Developing Drosophila Arousal Circuit Permanently Impairs Behavioral Responsiveness in Adults

The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the likelihood of this disorder in adulthood. To test this hypothesis in a high-throughput animal model, we have transiently manipulated dopamine sig...

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Bibliografische gegevens
Gepubliceerd in:Front Psychiatry
Hoofdauteurs: Ferguson, Lachlan, Petty, Alice, Rohrscheib, Chelsie, Troup, Michael, Kirszenblat, Leonie, Eyles, Darryl W., van Swinderen, Bruno
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Psychiatry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304146/
https://ncbi.nlm.nih.gov/pubmed/28243212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2017.00022
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