Identification of BPIFA1/SPLUNC1 as an epithelium-derived smooth muscle relaxing factor

Asthma is a chronic airway disease characterized by inflammation, mucus hypersecretion and abnormal airway smooth muscle (ASM) contraction. Bacterial permeability family member A1, BPIFA1, is a secreted innate defence protein. Here we show that BPIFA1 levels are reduced in sputum samples from asthma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Wu, Tongde, Huang, Julianne, Moore, Patrick J., Little, Michael S., Walton, William G., Fellner, Robert C., Alexis, Neil E., Peter Di, Y., Redinbo, Matthew R., Tilley, Stephen L., Tarran, Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303822/
https://ncbi.nlm.nih.gov/pubmed/28165446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14118
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