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Structural determinants of the hyperalgesic activity of myotoxic Lys49-phospholipase A(2)
BACKGROUND: Bothropstoxin-I (BthTx-I) is a Lys49-phospholipase A(2) (Lys49-PLA(2)) from the venom of Bothrops jararacussu, which despite of the lack of catalytic activity induces myotoxicity, inflammation and pain. The C-terminal region of the Lys49-PLA(2)s is important for these effects; however, t...
Guardat en:
| Publicat a: | J Venom Anim Toxins Incl Trop Dis |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5303236/ https://ncbi.nlm.nih.gov/pubmed/28203248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40409-017-0099-6 |
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