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A role for activated Cdc42 in glioblastoma multiforme invasion

Cdc42 is a Rho-GTPase which plays a major role in regulating cell polarity and migration by specifying the localization of filopodia. However, the role of Cdc42 in GBM invasion has not been thoroughly investigated. We generated stable doxycycline-inducible clones expressing wild type (WT)-, constitu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Okura, Hidehiro, Golbourn, Brian J., Shahzad, Uswa, Agnihotri, Sameer, Sabha, Nesrin, Krieger, Jonathan R., Figueiredo, Carlyn A., Chalil, Alan, Landon-Brace, Natalie, Riemenschneider, Alexandra, Arai, Hajime, Smith, Christian A., Xu, Songli, Kaluz, Stefan, Marcus, Adam I., Van Meir, Erwin G., Rutka, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302965/
https://ncbi.nlm.nih.gov/pubmed/27486972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10925
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