Targeting Zfp148 activates p53 and reduces tumor initiation in the gut

The transcription factor Zinc finger protein 148 (Zfp148, ZBP-89, BFCOL, BERF1, htβ) interacts physically with the tumor suppressor p53, but the significance of this interaction is not known. We recently showed that knockout of Zfp148 in mice leads to ectopic activation of p53 in some tissues and cu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nilton, Anna, Sayin, Volkan I., Zou, Zhiyuan V., Sayin, Sama I., Bondjers, Cecilia, Gul, Nadia, Agren, Pia, Fogelstrand, Per, Nilsson, Ola, Bergo, Martin O., Lindahl, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302905/
https://ncbi.nlm.nih.gov/pubmed/27487143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10899
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