Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway

Recent data suggest that the transcription factor Zfp148 represses activation of the tumor suppressor p53 in mice and that therapeutic targeting of the human orthologue ZNF148 could activate the p53 pathway without causing detrimental side effects. We have previously shown that Zfp148 deficiency pro...

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Publicado no:Sci Rep
Main Authors: Zou, Zhiyuan V., Gul, Nadia, Lindberg, Markus, Bokhari, Abdulmalik A., Eklund, Ella M., Garellick, Viktor, Patel, Angana A. H., Dzanan, Jozefina J., Titmuss, Ben O., Le Gal, Kristell, Johansson, Inger, Tivesten, Åsa, Forssell-Aronsson, Eva, Bergö, Martin O., Staffas, Anna, Larsson, Erik, Sayin, Volkan I., Lindahl, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7447789/
https://ncbi.nlm.nih.gov/pubmed/32843651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70824-2
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