Targeting Zfp148 activates p53 and reduces tumor initiation in the gut

The transcription factor Zinc finger protein 148 (Zfp148, ZBP-89, BFCOL, BERF1, htβ) interacts physically with the tumor suppressor p53, but the significance of this interaction is not known. We recently showed that knockout of Zfp148 in mice leads to ectopic activation of p53 in some tissues and cu...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Nilton, Anna, Sayin, Volkan I., Zou, Zhiyuan V., Sayin, Sama I., Bondjers, Cecilia, Gul, Nadia, Agren, Pia, Fogelstrand, Per, Nilsson, Ola, Bergo, Martin O., Lindahl, Per
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302905/
https://ncbi.nlm.nih.gov/pubmed/27487143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10899
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