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Mechanism of BRG1 silencing in primary cancers
BRG1 (SMARCA4) is a documented tumor suppressor and a key subunit of the SWI/SNF chromatin remodeling complex that is silenced in many cancer types. Studies have shown that BRG1 is mutated in cancer-derived cell lines, which led to the assertion that BRG1 is also mutated in primary human tumors. How...
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| Vydáno v: | Oncotarget |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5302903/ https://ncbi.nlm.nih.gov/pubmed/27486753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10593 |
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