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HBV suppresses expression of MICA/B on hepatoma cells through up-regulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance

Decreased expression of NKG2D ligands on HBV-infected human hepatoma cells impairs NK cells lysis. However, which components of HBV exert this effect and the precise mechanisms need to be further investigated. In the present study, we observed that the HBx and HBc genes significantly down-regulated...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Guan, Yun, Li, Weiqun, Hou, Zhaohua, Han, Qiuju, Lan, Peixiang, Zhang, Jian, Tian, Zhigang, Zhang, Cai
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302899/
https://ncbi.nlm.nih.gov/pubmed/27528231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11271
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