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The Proteasome Inhibition Model of Parkinson’s Disease

The pathological hallmarks of Parkinson’s disease are the progressive loss of nigral dopaminergic neurons and the formation of intracellular inclusion bodies, termed Lewy bodies, in surviving neurons. Accumulation of proteins in large insoluble cytoplasmic aggregates has been proposed to result, par...

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Bibliografski detalji
Izdano u:J Parkinsons Dis
Glavni autori: Bentea, Eduard, Verbruggen, Lise, Massie, Ann
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302045/
https://ncbi.nlm.nih.gov/pubmed/27802243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-160921
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