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The Proteasome Inhibition Model of Parkinson’s Disease
The pathological hallmarks of Parkinson’s disease are the progressive loss of nigral dopaminergic neurons and the formation of intracellular inclusion bodies, termed Lewy bodies, in surviving neurons. Accumulation of proteins in large insoluble cytoplasmic aggregates has been proposed to result, par...
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| Publicado no: | J Parkinsons Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
IOS Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5302045/ https://ncbi.nlm.nih.gov/pubmed/27802243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-160921 |
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