A subset of virus-specific CD161(+) T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML

The establishment of long-lived pathogen-specific T cells is a fundamental property of the adaptive immune response. However, the mechanisms underlying long-term persistence of antigen-specific CD4(+) T cells are not well-defined. Here we identify a subset of memory CD4(+) T cells capable of effluxi...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Alsuliman, Abdullah, Muftuoglu, Muharrem, Khoder, Ahmad, Ahn, Yong-Oon, Basar, Rafet, Verneris, Michael R., Muranski, Pawel, Barrett, A. John, Liu, Enli, Li, Li, Stringaris, Kate, Armstrong-James, Darius, Shaim, Hila, Kondo, Kayo, Imahashi, Nobuhiko, Andersson, Borje, Marin, David, Champlin, Richard E., Shpall, Elizabeth J., Rezvani, Katayoun
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301823/
https://ncbi.nlm.nih.gov/pubmed/27821506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-713347
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