Evidence for B Cell Exhaustion in Chronic Graft-versus-Host Disease

Chronic graft-versus-host disease (cGvHD) remains a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). A number of studies support a role for B cells in the pathogenesis of cGvHD. In this study, we report the presence of an expanded population of CD19+CD21− B cells with...

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Publicado en:Front Immunol
Autores principales: Khoder, Ahmad, Alsuliman, Abdullah, Basar, Rafet, Sobieski, Catherine, Kondo, Kayo, Alousi, Amin Majid, Szydlo, Richard, Muftuoglu, Muharrem, Shaim, Hila, Apperley, Jane F., Gokdemir, Elif, Cooper, Nichola, Mehta, Rohtesh S., Marin, David, Champlin, Richard, Shpall, Elizabeth, Rezvani, Katayoun
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770573/
https://ncbi.nlm.nih.gov/pubmed/29375566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01937
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