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Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3

In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques. Also, in vitro studies with polarized macrophages...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Solanki, Sumeet, Dube, Prabhatchandra R., Birnbaumer, Lutz, Vazquez, Guillermo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301208/
https://ncbi.nlm.nih.gov/pubmed/28186192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42526
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