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Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages

Endoplasmic reticulum (ER) stress is a prominent mechanism of macrophage apoptosis in advanced atherosclerotic lesions. Recent studies from our laboratory showed that advanced atherosclerotic plaques in Apoe(−/−) mice with bone marrow deficiency of the calcium-permeable channel Transient Receptor Po...

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Detalhes bibliográficos
Main Authors: Solanki, Sumeet, Dube, Prabhatchandra R., Tano, Jean-Yves, Birnbaumer, Lutz, Vazquez, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166736/
https://ncbi.nlm.nih.gov/pubmed/25031020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00369.2013
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