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Reduced calcification and osteogenic features in advanced atherosclerotic plaques of mice with macrophage-specific loss of TRPC3
BACKGROUND AND AIMS: Recent in vitro studies have showed that in macrophages deletion of the non-selective Ca(2+)-permeable channel TRPC3 impairs expression of the osteogenic protein BMP-2. The pathophysiological relevance of this effect in atherosclerotic plaque calcification remains to be determin...
Shranjeno v:
| izdano v: | Atherosclerosis |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5835414/ https://ncbi.nlm.nih.gov/pubmed/29290366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2017.12.025 |
| Oznake: |
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