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Synaptotagmin-1 and synaptotagmin-7-dependent fusion mechanisms target synaptic vesicles to kinetically distinct endocytic pathways

Synaptic vesicle recycling is essential for maintaining normal synaptic function. The coupling of exocytosis and endocytosis is assumed to be Ca(2+)-dependent but the exact role of Ca(2+) and its key effector synaptotagmin-1 (syt1) in regulation of endocytosis are poorly understood. Here, we probed...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Li, Ying C., Chanaday, Natali L., Xu, Wei, Kavalali, Ege T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300960/
https://ncbi.nlm.nih.gov/pubmed/28111077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.12.010
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