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Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling

N-myristoylation is the covalent attachment of myristic acid to the N-terminus of proteins in eukaryotic cells. The Matrix domain (MA) of HIV-1 Gag protein is N-myristoylated and plays an important role in virus budding. In screening for host factors that interact with HIV-1 MA, we found that heme o...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Zhu, Yiping, Luo, Shukun, Sabo, Yosef, Wang, Cheng, Tong, Liang, Goff, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300893/
https://ncbi.nlm.nih.gov/pubmed/28132836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.01.002
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