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Optical Trapping Nanometry of Hypermethylated CPG-Island DNA
Cytosine methylation is a key mechanism of epigenetic regulation. CpG-dense loci, called “CpG islands”, play a particularly important role in modulating gene expression. Methylation has long been suspected to alter the physical properties of DNA, but the full spectrum of the evoked changes is unknow...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300791/ https://ncbi.nlm.nih.gov/pubmed/28109529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.029 |
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