Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain

Protein kinase A (PKA) plays critical roles in neuronal function that are mediated by different regulatory (R) subunits. Deficiency in either the RIβ or the RIIβ subunit results in distinct neuronal phenotypes. Although RIβ contributes to synaptic plasticity, it is the least studied isoform. Using i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Ilouz, Ronit, Lev-Ram, Varda, Bushong, Eric A, Stiles, Travis L, Friedmann-Morvinski, Dinorah, Douglas, Christopher, Goldberg, Jeffrey L, Ellisman, Mark H, Taylor, Susan S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2017
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300705/
https://ncbi.nlm.nih.gov/pubmed/28079521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17681
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