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High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila

Genomic sequencing has implicated large numbers of genes and de novo mutations as potential disease risk factors. A high throughput in vivo model system is needed to validate gene associations with pathology. We developed a Drosophila-based functional system to screen candidate disease genes identif...

詳細記述

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書誌詳細
出版年:eLife
主要な著者: Zhu, Jun-yi, Fu, Yulong, Nettleton, Margaret, Richman, Adam, Han, Zhe
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300701/
https://ncbi.nlm.nih.gov/pubmed/28084990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22617
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