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High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila
Genomic sequencing has implicated large numbers of genes and de novo mutations as potential disease risk factors. A high throughput in vivo model system is needed to validate gene associations with pathology. We developed a Drosophila-based functional system to screen candidate disease genes identif...
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| 出版年: | eLife |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300701/ https://ncbi.nlm.nih.gov/pubmed/28084990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22617 |
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